Yajuan Hao
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Education：
2011-2016 Beijing Institute of Genomics, Chinese Academy of Sciences Ph.D.
2007-2011 Hebei Normal University of Science and Technology B.S
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Career：
2020-present Shanghai Institute of Immunology Assistant Research Fellow
2016-2020 Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Postdoctoral Fellow
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Research Interests：
The role of RNA methylation modifications in anti-tumor immunity
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Publications：
(# First-author equivalent, * Corresponding-author equivalent):
1 Gao Y#, Wang Z#, Zhu YD#, Zhu Q, Yang Y, Jin YP, Zhang F, Jiang L, Ye YY, Li HF, Zhang YC, Liang HB, Xiang SS, Miao HJ, Liu YB*, Hao YJ*. NOP2/Sun RNA methyltransferase 2 promotes tumor progression via its interacting partner RPL6 in gallbladder carcinoma, Cancer Science 110 (11): 3510-3519 (2019)
2 Li ML#, Liu FT#, Zhang F#, Zhou WP#, Jiang XQ#, Yang Y, Qu K, Wang YQ, Ma Q, Wang T, Bai L, Wang Z, Song XL, Zhu YD, Yuan RY, Gao Y, Liu YC, Jin YP, Li HF, Xiang SS, Ye YY, Zhang YJ, Jiang L, Hu YP, Hao YJ, Lu W, Chen SL, Gu J, Zhou J, Gong W, Zhang Y, Wang XF, Liu XY, Liu C, Liu HB*, Liu Y*, Liu YB*, Genomic ERBB2/ERBB3 mutations promote PD-L1-mediated immune escape in gallbladder cancer: a whole-exome sequencing analysis, Gut 68 (6): 1024-1033 (2019)
3 Ye YY#, Mei JW#, Xiang SS#, Li HF, Ma Q, Song XL, Wang Z, Zhang YC, Liu YC, Jin YP, Hu YP, Jiang L, Liu FT, Zhang YJ, Hao YJ* and Liu YB*. MicroRNA-30a-5p inhibits gallbladder cancer cell proliferation, migration and metastasis by targeting E2F7. Cell Death and Disease 9 (3): 410 (2018)
4 Yang X#, Yang Y#, Sun BF#, Chen YS#, Xu JW#, Lai WY#, Li A, Wang X, Bhattarai DP, Xiao W, Sun HY, Zhu Q, Ma HL, Adhikari S, Sun M, Hao YJ, Zhang B, Huang CM, Huang N, Jiang GB, Zhao YL, Wang HL*, Sun YP*, Yang YG*, 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader, Cell Research 27 (5):606-625 (2017)
5 Xiao W#, Adhikari S#, Dahal U#, Chen YS#, Hao YJ#, Sun BF#, Sun HY, Li A, Ping XL, Lai WY, Wang X, Ma HL, Huang CM, Yang Y, Huang N, Jiang GB, Wang HL, Zhou Q, Wang XJ, Zhao YL, Yang YG*. Nuclear m6A reader YTHDC1 regulates mRNA splicing. Molecular Cell 61 (4): 507-519 (2016)
6 Sun HY#, Hao YJ#, Ping XL, Huang CM, Yang Y, Sun BF, Yang YG*. Dynamics and biological significance of RNA methylations. Chinese Bulletin of Life Sciences 28 (5): 1-12 (2016)
7 Chen T#, Hao YJ#, Zhang Y#, Li MM#, Wang M, Han WF, Wu YS, Lv Y, Hao J, Wang LB, Li A, Yang Y, Jin KX, Zhao X, Li YH, Ping XL, Lai WY, Wu LG, Jiang GB, Wang HL, Sang LS, Wang XJ*, Yang YG*, Zhou Q*. m6A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency. Cell Stem Cell 16 (3): 289-301 (2015)
8 Zhao X#, Yang Y#, Sun BF#, Shi Y#, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, Wang X, Huang CM, Fu Y, Ge XM, Song SH, Jeong H, Yanagisawa H, Niu YM, Jia GF, Wu W, Tong WM, Okamoto A, He C, Danielsen J, Wang XJ, Yang YG*. FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis. Cell Research 24 (12): 1403-1419 (2014)
9 Zheng GQ#, Dahl JA#, Niu YM#, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu ZK, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia GF, Zhao X, Liu J, Krokan HE, Klungland A*, Yang YG*, He C*. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Molecular Cell 49 (1): 18-29 (2013)
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